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In clinical practice, several conditions may contribute to new or worsening breathlessness, including: Autonomic dysfunction such as POTS Babesia co-infection Lyme carditis Immune-mediated respiratory inflammation Asking the Right Questions When evaluating Lyme-related dyspnea, several questions become important: Does the breathlessness occur at rest, with exertion, or while lying down

reviewed the literature and drafted the original version of the manuscript

Acute lung Injury/Acute respiratory distress syndrome Up to 78% of patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) experience long-term cognitive impairment, primarily characterized by memory deficits and executive dysfunction [43, 44]

3.2.2.1 Basic science research In animal models of PD, GIP analogs showed promising results with improvement in motor symptoms and reduction of the inflammation response (Li et al., 2016)