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To maintain a moderate weight, also try to eat more healthfully and engage in regular exercise.

It should be noted that not only GSK3, but also other kinases, such as AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin complex 1 (mTORC1), directly or indirectly regulate Nrf2 stability and activity (Silva-Islas and Maldonado, 2018)
