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Journal of Inorganic Biochemistry

3.1.1 Topoisomerase inhibitors Topoisomerase inhibitors are a class of anticancer drugs whose mechanism of action is based on blocking topoisomerase enzymes from re-ligating the DNA strands after supercoiling, thus preventing DNA replication [61]

A true hiatal hernia is a gastric pathology and occurs when part of the stomach protrudes through the opening of the diaphragm where the esophagus normally passes through, taking up space normally reserved for the heart and the lungs

This mechanistic overlap raises theoretical questions about additive benefit, though emerging evidence suggests that exogenous GLP-1 agonists can produce additional weight loss even in the altered post-surgical gut hormone environment