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In vitro experiments revealed no cytotoxic effects of DNAzymes and DNZ-NLPs on SH-SY5Y cells even in high concentrations of 100 and 200 g/mL, emphasizing the systems potential
Glaucomatous optic neuropathy takes time to develop, and hence the disease is known to be progressive
Because of the incomplete clinical evidence on their effectiveness, safety, and social consequences in the case of long-term use, especially with synthetic variants of these drugs, they cannot be recommended to healthy individuals who do not suffer from any cognitive dysfunction
doi: 10.1016/j.phrs.2016.07.008
