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The University of Michigan also warns that a B12 shot is not recommended for people with Lebers disease (7)
(7.1) Drugs Associated with Methemoglobinemia: Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs
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