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Similarly, PNPLA3 I148M promotes hepatosteatosis through ABHD5-dependent inhibition of PNPLA2 (75), suggesting that small molecules that target the PNPLA3 I148M/ABHD5 interaction could be potential therapeutics for FLD and diabetes

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Matos IV, Castejon E, Meavilla S, OCallaghan M, Garcia-Villoria J, Lopez-Sala A, et al

Levels typically need to be checked before and during pregnancy to guide dosing
