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Description
In a study using a rotenone-induced PD mouse model, combined with antibiotic-induced microbiome depletion and fecal microbiota transplantation, it was found that gut microbiota dysbiosis, along with leaky gut-induced bacterial endotoxins, activates C/EBP/AEP signaling and -syn pathology, ultimately leading to neurodegeneration in PD (52)
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