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TABLE 1 Role of ferroptosis in neurodegenerative diseases

Bottom Line Standard reduced glutathione can increase body stores with consistent oral use, although results vary
56 However, if the patient continues to present evidence of liver dysfunction beyond persistent ALT elevation (satisfying KCH criteria of acidosis, elevated creatinine, hyperbilirubiniemia, coagulopathy and encephalopathy), then NAC therapy should be continued as these indicators portend a poor prognosis regardless of transaminase levels