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Diclofenac can be formulated with cyclodextrins as suppositories to improve release and absorption through the rectal mucosa [146]

The drug, which was originally developed at Karuna Therapeutics, began its development journey as an investigational treatment at Eli Lilly for Alzheimers disease, where its effects on the psychotic symptoms of the disease where discovered

Liu Y, Wang H

Inactivation of oncogenes such as viral myelocytomatosis oncogene or Human Epidermal Growth Factor Receptor 2 (HER2) can trigger an anti-tumor immune response