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SsTyrA a D208N showed significant PDH activity that was absent in Wt, though its K m was still much higher than previously reported TyrA enzymes (Rippert and Matringe, 1)
35 Compared to GLS2, GLS1 is predominantly expressed in the brain

Psychiatry 14 , 209 (2024)

Although the explicit role of iron in glucose metabolism remains elusive, these insights imply that glucose is the major metabolic regulator during iron perturbations
