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This, in turn, affects lipid metabolism and inflammatory responses

doi: 10.20463/jenb.2018.0026

Quaking proteins (QKI) Recent research has revealed that the QKI protein, which is downregulated in a spectrum of malignant tumors such as lung, gastric, and CRC, 314,315,316,317 and serves as a tumor suppressor in various human cancers, encompassing oral, colon, gastrointestinal, and prostate cancer 318,319 (Fig

With the progress of clinical trials such as KEYNOTE-426, the combined use of immune checkpoint and protein tyrosine kinase inhibitors is now one of the standard treatment options for most patients with metastatic RCC (150)