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Description
Ionizing Radiation for Preparation and Functionalization of Membranes and Their Biomedical and Environmental Applications

The human pancreatic tumor cell line PANC-1 was purchased from (Wuhan Doctoral Bioengineering Co., Ltd, Wuhan, China), MIA PaCa-2 was purchased from (iCell Bioscience Inc, Shanghai, China), ASPC-1 and human normal pancreatic ductal epithelial cells HPNE were preserved in the Medical Research and Experimental Centre of Yan'an University (Yan'an, China)

Other contributing factors include nutritional deficiencies, skin injuries, and underlying medical conditions, all of which can lead to hyperpigmentation in this area

More importantly, within plaques, oxidative stress and CD40-TRAF6 signaling form positive feedback loops
