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In experimental studies, formation of complexes of cellular antigen with antibody resulted in activation of dendritic cells, facilitation of cross-presentation of antigens to tumor-specific CD 8 + T cells and inhibition of tumor growth Fc receptor-targeted antigen uptake was shown to initiate cross-presentation pathways as an immune regulatory mechanism for effective tumor immunity

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1,3 Furthermore, they are contraindicated in individuals with glaucoma, benign prostatic hypertrophy, and dementia

bioRxivJanuary 06, 2022