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Endothelial cell tube formation assay To examine the effect of BPC-157 on angiogenesis in vitro, tube formation assay was performed as described previously

As for treatment protocol, wound treatments were applied once daily, before re-bandaging, for 21 days

Then, rVSV/SARS-CoV-2/GFP2E1 populations containing 10 6 infectious units were incubated with individual antibodies (at 1.25, 2.5, 5 or 10 g ml 1 final concentration) or 1:1 mixtures of two antibodies (5 g ml 1 of each antibody) for 1 h at 37 C

Over 100 published preclinical studies have demonstrated protective and reparative effects of BPC-157 across tendon, muscle, bone, and gastrointestinal tissue