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Abstract Mitochondria are the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS), most of them originating from the mitochondrial respiratory chain

67 MadiganSMTraceyFMcNultyHEaton-EvansJCoulterJMcCartneyHet alRiboflavin and vitamin B-6 intakes and status and biochemical response to riboflavin supplementation in free-living elderly people
Following oral, intravenous, or intraperitoneal administration, curcumin is predominantly metabolized to glucuronide and sulfate conjugates in the liver and excreted via bile into the gastrointestinal tract (176, 177)

Iron is indispensable for oxygen transport, mitochondrial respiration, enzymatic activity, neurotransmitter production, thyroid hormone metabolism, immune competence, and skeletal muscle performance