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Description
Although liver support devices did not show promising results in the management of patients with acute-on-chronic liver failure, a trend towards their efficacy has been associated with their use as part of the advanced management of ALF patients [5,6]

However, the practical application of external NO therapies in clinical settings has relied on industrial NO cylinders, which present several challenges

Alternate use or apply actives at different times of day (e.g., Vitamin C in the morning, Copper Peptides at night)

As a result, reviewers generally describe these findings as suggestive rather than definitive
