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Although long-term endurance training and the late recovery phase after acute bouts tend to promote M2-like macrophage polarization, the early phase following acute exercise is dominated by the mobilization of pro-inflammatory monocytes and an increase in M1-like macrophage infiltration, particularly in skeletal muscle tissues (3941)

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This raises the BBBs permeability and promotes the unregulated entry of cytokines, immune cells and other inflammatory indicators, thereby altering the tightly regulated neuronal milieu (Rubin and Staddon, 1999

Potentilla chinensis A traditional Chinese medications source plant, Potentilla chinensis , has been investigated for pharmacological activity