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Tight regulation of these pathways ensures a balance between energy generation and nitrogen conservation [46]

Cardiolipin is tightly associated with ATPase pumps ( Remarkably, PUFAs that are deuterated at their bis-allylic carbon atoms have been found to be highly effective at quenching the chain reaction and suppressing the inflammatory response

Using a scientific yet accessible tone, we review how these therapies work, the clinical evidence supporting their use in EDS patients, and important considerations regarding their safety and limitations

doi: 10.1186/s12967-016-0831-y