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[DOI] [PMC free article] [PubMed] [Google Scholar] Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T, Yu ZX, Ferrans VJ, Howard BH, Finkel T

Yes, it may help reduce dark spots and promote an even complexion, leading to a more radiant appearance

Specifically, ROS can oxidize and inactivate MAPK phosphatases (MKPs), which normally dephosphorylate and deactivate MAPKs
For instance, miR-16 -loaded minicell is in clinical investigation for the treatment of malignant pleural mesothelioma (229)