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Pretty dissapointing stats for the CNHL G+ series, I guess I won't be getting another one

Many nuclear receptors retain full ligand-dependent transcriptional activity by binding to coactivators containing short leucine-rich LxxLL motifs (where x can be any amino acid) known as nuclear receptor (NR) boxes 78

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Total symptom score decreased significantly compared to placebo across treatment groups of all doses 600-1800 mg/d oral ALA, yet there was a dose-dependent increase in nausea, vomiting, and vertigo, and therefore the lowest dose of oral ALA (600 mg/d) is recommended