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They have to bypass the gut entirely

Indeed, elevated homocysteine is now recognized as a strong risk factor for cognitive impairment and dementia, including Alzheimers disease (66-68)

Everyone responds differently, but many people find it helps them feel more in control of cravings, steadier during the day, and more consistent with reaching their goals

If any step in that chain is impaired, deficiency develops even if your diet looks fine on paper
