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Description
TZP affected the enzyme activity of PFKFB3 and PFK1 which are engaged in the ratelimiting step in glucose metabolism (Figure 5KN)

However, Garg added that the real-world data show the potential benefits incretin-based medications could provide for the type 1 diabetes population
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American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines for medical care of patients with obesity

New England Journal of Medicine , 387 (3), 205216
