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Tirzepatide (Mounjaroand Zepbound), aGLP-1andGIPreceptor agonist, has recently gained significant popularity for itsweight loss benefits

In the present work, we have designed a context-based dynamic metabolic model to establish that the coordinated functioning of glutathione peroxidase (GTHP), glutathione oxidoreductase (GTHO) and NADPH oxidase (NOX) is crucial in determining cancerous transformation, specifically in gliomas

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