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However, once LCR was tested alone using the same dosage, but for a longer period (i.e., 24 wk), no significant effect was found

doi: 10.1001/archneur.1994.00540200063018

The weakest part of the argument is that no clinical trial has ever tested this specific combination, the additive effect of levocarnitine on top of tirzepatide substantial metabolic impact may be negligible, and the cost premium is not clearly justified by the expected benefit
