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However, GNK-301, compared to autoantibodies, has the huge advantage of displaying a much greater affinity and neutralizing effect
To assess whether the HIF-dependent potentiation of cell death is due to synergizing with compounds that reduce GSH pools, we used buthionine sulfoximine (BSO), which inhibits de novo GSH biosynthesis
Determination of subcutaneous tumor size in athymic (nude) mice
Redox imbalance is a key pathogenic mechanism in melanoma and non-melanoma skin cancers, with activation of the NRF2-ARE pathway acting as an intrinsic defense against oxidative stress
