glutathione role in sulphur metabolism NFIXNa The Glutathione System: A Journey

Description

[7] Administration therefore restores physiologic androgen levels, suppresses hypothalamic gonadotropin-releasing hormone and pituitary luteinizing hormone, stabilizes nitrogen balance, increases lean body mass and may improve mood and sexual function, yet prolonged suppression of intratesticular testosterone can reduce spermatogenesis, underscoring the need for careful dose titration and fertility counseling when indicated

GH-axis manipulation can complicate insulin sensitivity and fluid balance in some individuals

GSH is most accurately quantified using a J-edited MEGAPRESS sequence with a longer TE, 6,17,18 which enable the differentiation of extended versus closed GSH forms in the brain