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Chem.-Bio

obtained a pyrazolone small molecule compound (C646) through virtual screening, which has been demonstrated to inhibit tumor proliferation, promote tumor apoptosis, alter glucose metabolism, reduce tumor drug resistance and induce tumor immune response in different kinds of cancers

doi: 10.1097/00005344-200405000-00013

The extrahepatic bile duct can harvest primary brown pigment stones which typically develop in obstructed and infected bile ducts, as well as secondary stones from the gallbladder made of pure cholesterol or mixed type (choledocholithiasis)
