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Three SAM molecules are required for the methylation of phosphatidylethanolamine to phosphatidylcholine by phosphatidylethanolamine N-methyltransferase (PEMT)

The second method of import is by a betaine/choline/carnitine transporter (BCCT) that can be driven by the sodium or proton motive force, but in many cases where carnitine is the substrate often functions as a carnitine: -butyrobetaine antiporter (Ziegler et al