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Description
All of these family members have a Rel-homology (RHD) domain that is essential for DNA binding and dimerization

For instance, not all cancer subtypes are amenable to KD

Therefore, metabolic pathways of iron, glucose and fat seem to interplay with each other both in a physiological and pathologic status

At the molecular level, S6K1 enhances the efficiency of MYC translation by regulating phosphorylation of the eukaryotic initiation factor eIF4B