glutathione transferases S-transferase Human glutathione transferases catalyze the

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In the laboratory of allergic diseases 2 (LAD2) human mast cell line, quercetin reduced Substance P- and C48/80 (a compound used to promote histamine release from mast cells in experiments)-induced calcium flux in a dose-dependent manner, with concentrations above 100 M demonstrating effects comparable to dexamethasone at 100 M

Graf and Kastin, who authored the two most comprehensive reviews of DSIP biology (1984 [4] and 1986 [5]), documented extensive preclinical effects without being able to trace them to a single receptor