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Introduction Nutritional deficiency is an emerging global crisis in the developing and the developed world which cause deficiencies in growth, immune functions, cognitive and motor progress, behavior, and intellectual performances in humans specially children

These include high target specificity and selectivity that can increase potency while reducing off-target toxicity, and a low propensity for drugdrug interactions because they are catabolized to amino acids rather than competing for small-molecule metabolic pathways [4]

EH: Formal analysis, Investigation, Methodology, Writing original draft

Most studies on the nasal delivery of antidiabetic peptides, such as insulin, exendin-4, and GLP-1 with CPPs confirmed the effectiveness of the simple physical mixing of CPP with cargos in vivo