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doi: 10.1007/s12011-010-8840-9
214 Interesting, IREs are found in the 5-UTR of amyloid precursor protein (APP) and -synuclein (-Syn) transcripts, and iron accumulation can upregulate the levels of -Syn, APP and amyloid -peptide (A)
For example, a study of coronary artery patients indicated that genomic DNA methylation directly correlates with folate status and inversely with plasma homocysteine levels
However, exactly how the renal filter works and why its permeability is altered in kidney diseases is poorly understood
