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Description
Before excretion, TMAOand any unmetabolized TMAenters the plasma and is transported to body tissues (such as the lungs, liver, kidneys, muscles, and heart) where it accumulates as an osmolyte compound

These drugs not only help lower blood sugar but also promote weight loss and may improve cardiovascular outcomes

doi: 10.1111/liv.15930 89

Increased plasma and urinary level of porphobilinogen are seen during acute episode, whereas during remission values may normalize (3, 8)
