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C3a and C5a are critical immunomodulators that, in addition to serving as anaphylatoxins, also function as potent immunomodulatory agents through their cognate receptors (C3aR, C5aR1, and C5aR2 or C5L2), which are expressed on various innate and adaptive immune cells

While the exact role of glutathione has not been completely defined, it is clear that, depending on its redox state, glutathione can react with various intracellular molecules and that glutathionylation/deglutathionylation reactions of both proteins and smaller compounds are central to GSH functions

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[DOI] [PMC free article] [PubMed] [Google Scholar] Windham, I