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Open discussion between patients and their practitioners about these risks and benefits can facilitate shared decision-making around the use of dietary supplements that can optimize the benefits while minimizing harm through careful selection of supplements (if used at all) and close monitoring for both adverse effects and improvement in desired endpoints

Although ARE/EpRE, AP-1 and NFB may be responsible for basal expression and induction of GCLC by many of the pro- and anti-oxidants, recently c-Myc has been identified to also contribute to the basal expression and induction of human GCL under oxidative stress (Benassi et al., 2006)

[DOI] [PubMed] [Google Scholar] Zala, D

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