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Furthermore, a notable rise in the expression levels of genes associated with autophagy, as well as a higher quantity of autophagic vacuoles and lysosomes, has been detected in degenerated intervertebral discs and the annulus fibrosus (181, 182)

Protect skin cells from oxidative damage and toxins

Then, we investigated whether DRD2 activation upregulates Nrf2 targets in primary astrocytes

Under normal, resting conditions reactive oxygen species are removed from the cell preventing any subsequent damage