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10.1038/s41598-021-98887-9 18 CenY.ZouX.ZhongQ.ChenY.LinY.FengQ.et al (2022)

Acne has many causes, including: Build-up of bacteria Overproduction of sebum, which clogs pores Hormonal imbalances Gut imbalances Genetics Smoking Stress Dietary triggers like dairy, sugar, and highly processed foods Comedogenic skin care products Skin barrier damage Also associated with the development of acne is oxidative stress, which doesnt occur only after breakouts rear their head

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(2022) indicated a significant increase of basic sperm parameters including sperm concentration, total motility, progressive motility and normal forms following AOX therapy versus placebo or no treatment (100)