foxo4 dri peptide senolytic mouse study 2023 inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis FOXO4-DRI induces keloid senescent fibroblast
Description
Dnges L, Damle A, Mainardi A, Bock T, Schnenberger M, Martin I, et al
Human iPSCs were adapted onto feeder-free conditions by plating on Geltrex (Thermo Fisher Scientific, Rockford, IL) coated plates, and fed daily with mTeSR medium (Stem Cell Technologies, Vancouver, Canada) at 37C 5% CO 2
Temperature proves critical
phospho-Thr167) 23 and the maintenance of S phase checkpoint related BID (phospho-Ser78) 24 protein were decreased (FC = 0.83 and 0.72) (Fig
