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Other biochemical measurement methods, such as liquid chromatographymass spectrometry or automated clinical analyzers for lipids or other metabolites may be more readily available than developing a custom ligand binding method

It is noteworthy that cerebral ischemic injury can lead to vascular dementia (VD)

energetic dysmetabolism and correct glucose levels in blood are necessary for maintaining a physiological pregnancy [10]

As mentioned at top, neither quinacrine nor chlorpromazine actually works in vivo against any prion strain as far as we know, so I debate whether understanding their MoA is A) an irrelevant distraction, or B) critical for understanding why they dont work and for finding compounds that do