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doi:10.1002/ptr.8189 78

Typically, oxidation proceeds by adding oxygen to a foreign compound (e.g., hydroxyl group insertion in benzene to form phenol) or, alternatively, by removing hydrogen atoms from a molecule (e.g., ethanol from alcoholic beverages is converted to acetaldehyde by alcohol dehydrogenase) (Figure 3)

However, the knockdown of SIRT2 results in significant enhancement of cell proliferation activity and decreased apoptosis

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia