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It's main mechanistic outcomes are Targeted fat loss: Designed to promote lipolysis (fat breakdown) and inhibit lipogenesis (fat formation)

In KEEPS, women with normal transporter activity had lower circulating levels of estrone and 17estradiol sulfate than those with lower activity, while those with reduced transporter activity demonstrated a greater decrease in night sweats among women on active treatment.55 Additional research using larger cohorts of women is needed in order to utilized a pharmacogenomic approach to maximize hormone treatments

Halegoua-DeMarzio, D., Navarro, V., Ahmad, J., Avula, B., Barnhart, H., Barritt, A

A pea-sized amount is enough for the entire face