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Results Screening for genes that promote copper toxicity in a cell model of Wilson disease To find new genes that might be targeted for reduction of Cu toxicity in Wilson disease we employed genome-wide shRNA screening in ATP7B-KO HepG2 cells, a bona fide WD cell model 12,13

43 Du PreezI.LootsD

Discovery and Validation of potential serum biomarkers with pro-inflammatory and DNA damage activities in ulcerative colitis: a comprehensive untargeted metabolomic study

The so-called Warburg effect (or aerobic glycolysis) has become a well-known and common metabolic phenotype allowing tumors to fulfil the energetic requirement for cell growth [3]