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The shared features among these nuclear receptors that regulate metabolism, such as the response element configuration and interacting with an RXR heterodimer partner, may promote some of the crosstalk observed between TR mediated TH and nutrient pathways (157)

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Despite a long-standing tendency to dismiss or downplay SSRI discontinuation syndrome, these SSRI withdrawals can last up to a year or longer, especially where the timeline for SSRI withdrawal was too abbreviated, or not well-supported