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[77] A major mechanism of withdrawal from tricyclic antidepressants is believed to be due to a rebound effect of excessive cholinergic activity due to neuroadaptations as a result of chronic inhibition of cholinergic receptors by tricyclic antidepressants

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However, the research was conducted solely on the Korean population whose metabolic characteristics related to BMI and T2DM could be different from those of other ethnicities, thus requiring further evaluations (Jeong et al., 2020)

f , i , Proposed fragmentation pathways of flavan-3,3,4-triol ( 4 ) for fragments observed in negative ( f ) and positive ( i ) ion ESI-MS
