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[DOI] [PubMed] [Google Scholar] Banerjee TD, Middleton F, Faraone SV
In PCOS, high LH can cause FSH signaling pathway defects and interfere with glucose uptake and glycogen synthesis in granulosa cells, resulting in follicular growth arrest and ovulation disorders (72)
The specific pathogenesis begins with the imbalance between the generation and clearance of ROS within cells
A limitation of the study was the small sample size and the lack of investigation into whether CAL02s efficacy is concentration-dependent
