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PubMed Central, Lahner, Edith, et al
Oral administration at 100150mg to match subcutaneous bioavailability doubles the per-dose cost, which influences protocol design when budget constraints exist

In those situations, professionalgrade supplements or B12 injections are often recommended to prevent deficiency. When to Consider Vitamin B12 Injections You may be a good candidate for vitamin B12 injections if you have a confirmed deficiency, ongoing fatigue, known absorption problems, or dietary patterns that make it hard to get enough B12 from food alone

Half-Life: AOD 9604 2 mg has a relatively short half-life, typically estimated to be around 2-3 hours
