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The presence of elevated blood pressure and impaired fasting glucose in this overweight patient strongly suggests underlying metabolic syndrome
44,45 IRE (iron response element) /IRP (iron regulatory protein) axis plays critical role in maintaining iron homeostasis through posttranscriptional regulation of iron-related genes

doi:10.1002/hep.1840090324

Other symptoms include pelvic pressure or pain, frequent urination, difficulty emptying the bladder, and constipation
