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In addition to protecting energy metabolism from high glucose disruption, this compound can also reduce mitochondrial damage and maintain mitochondrial membrane potential through ROS suppression and mitophagy stimulation (Figure 1

At day 3 of adulthood worms were picked, washed with PBS and stained with 5 M of dihydroethdium (DHE, Invitrogen) in PBS for 45 min at 20 C with agitation

If you experience any severe symptoms outside of minor swelling or bruising at the injection site, including significant pain at the injection site that has not gone away by the next day, call your doctor immediately.