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Orthomolecular Medicine, 2001, 16(3):177-182 We demonstrated that ascorbate administration in guinea pigs reduced tumor growth rates, and that intra-tumor concentrations in the millimolar range were attained

The intricate interaction between the HPA axis, neuroinflammation, mitochondrial functioning and oxidative stress might be crucial in mechanisms underlying the beneficial effects of the nutritional interventions in the context of ES

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Its primary distinction is its dual-pathway mechanism (VEGFR2 + NO) combined with its gastric stability making it the only compound in this group with demonstrated activity when administered orally in animal models, not just by injection