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Regulated NO signaling can support normal endothelial signaling homeostasis, while excessive or dysregulated NO production can interact with reactive oxygen species and contribute to oxidative or nitrosative stress

It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside

Here we investigated whether DHA itself or select metabolites can account for its antitumor action